Select a medication and discuss the ethnic, cultural, or genetic differences in the use and consideration for cancer pain. Share the mechanism of action of this medication and hints for monitoring side effects and drug interactions, including interactions with CAM. Discuss evidence and treatment guidelines to determine appropriate therapeutic options for a patient with cancer pain. Elaborate on a pain management strategy for adequate pain management. Include your references in APA format.
Bleomycin is a medication used to treat Hodgkin’s lymphoma, testicular cancer, and cervical cancer among other cancer diseases. The medication acts by binding to the guanosine-cytosine-rich portions of the DNA through the S tripeptide and so induces the DNA strand breaks (DeHart et al., 2021). Alternatively, the drug is also associated with the inhibition of the thymidine portion into the DNA strand. The common side effects of the medication include weight loss, hair loss, and redness of the skin. According to Calaway, et al. (2018), the medication is likely to induce pneumonitis and pulmonary fibrosis; therefore, the patients should be closely monitored for such complications. In addition, some patients develop hypersensitivity. Hypersensitive reactions can be fatal and thus must be monitored as well.
Bleomycin interacts with brentuximab, digoxin, and gentamycin among other antibiotics. The medication’s therapeutic efficacy also tends to reduce when taken together with the herbal medications. In some cases, the concentration of bleomycin in the serum may increase and cause toxicity. In case of interactions, the healthcare providers should stop the medications and address the patient’s symptoms. The goal of the therapeutic plan and administration is to reduce adverse reactions and improve the patient’s health outcomes. Therefore, the patient’s symptoms ought to be monitored for possible adverse reactions and appropriate remedies initiated. Watson (2018) provided guidelines that the medication can be administered intravenously or intramuscularly. The recommended dose of 225 x103 IU should be given.
ORDER A PLAGIARISM FREE-PAPER HERE
Finally, genetic and ethnic factors affect the therapeutic outcomes of the medication. Poor adherence to the prescription due to religious and cultural factors could lower the efficacy of the drug. Alternatively, cases of hypersensitivity have been reported and they are linked to immunogenic reactions due to genetic factors.
References
Calaway, A. C., Foster, R. S., Adra, N., Masterson, T. A., Albany, C., Hanna, N. H., Einhorn, L. H., & Cary, C. (2018). Risk of bleomycin-related pulmonary Toxicities and operative morbidity after Postchemotherapy Retroperitoneal lymph node dissection in patients with good-risk germ cell tumors. Journal of Clinical Oncology, 36(29), 2950-2954. https://doi.org/10.1200/jco.18.00431
Struggling to meet your deadline ?
Get assistance on
Select a medication and discuss the ethnic, cultural, or genetic differences in the use and consideration for cancer pain. Share the mechanism of action of this medication and hints for monitoring side effects and drug interactions, including interactions with CAM. Discuss evidence and treatment guidelines to determine appropriate therapeutic options for a patient with cancer pain. Elaborate on a pain management strategy for adequate pain management. Include your references in APA format.
done on time by medical experts. Don’t wait – ORDER NOW!
DeHart, A. N., Mack, J. M., Garner, A., Nicholas, R., Smith, A., Lewis, P. S., & Crary, S. E. (2021). Surveillance chest X-ray and pulmonary function testing in patients undergoing Intralesional Bleomycin in the treatment of vascular malformations. Journal of Vascular Anomalies, 2(4), e024. https://doi.org/10.1097/jova.0000000000000024
Watson, R. A., De La Peña, H., Tsakok, M. T., Joseph, J., Stoneham, S., Shamash, J., Joffe, J., Mazhar, D., Traill, Z., Ho, L., Brand, S., & Protheroe, A. S. (2018). Development of a best-practice clinical guideline for the use of bleomycin in the treatment of germ cell tumors in the UK. British Journal of Cancer, 119(9), 1044-1051. https://doi.org/10.1038/s41416-018-0300-x
ORDER A PLAGIARISM FREE-PAPER HERE
please respond to question below minimum 250 words thank you
Select a medication and discuss the ethnic, cultural, or genetic differences in the use and consideration for cancer pain. Share the mechanism of action of this medication and hints for monitoring side effects and drug interactions, including interactions with CAM. Discuss evidence and treatment guidelines to determine appropriate therapeutic options for a patient with cancer pain. Elaborate on a pain management strategy for adequate pain management. Include your references in APA format.