Managing Chlamydia Essay

Managing Chlamydia Essay

Managing Chlamydia Essay

Chlamydia is among the sexually transmitted infections caused by a bacteria, chlamydia trachomatis. The bacteria have two infectious stages including the elementary body and the reticulate body. Chlamydia trachomatis is a gram-positive bacteria that replicate in the eukaryotic cells. The bacteria target the squamocolumnar epithelial cells in the upper urinary tract and endocervix regions (Adachi et al., 2021). The developmental forms, elementary and reticulate forms, utilize the nutrients of the host cells to reproduce through binary fusion. The excess production of the elementary body causes cytolysis (Adachi et al., 2021). Patients with chlamydia present with painful urination, vaginal discharge, testicular pain, and discharge from the penis in men (Käding et al., 2021).

The treatment options for chlamydia include the use of antibiotics and painkillers to manage the pain. The antibiotics used include azithromycin and doxycycline. Alternatively, tetracycline, erythromycin, and ofloxacin may also be used. All the medications are administered for seven days except for azithromycin which is given as a single dose of 1 gram (Jin, 2021). The effectiveness of the treatment options may vary from one person to another. Therefore, the healthcare providers ought to explore the best option for the patient depending on their treatment history.

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The study conducted by Macaux et al. (2020) indicates the effectiveness of the seven-day dose of doxycycline compared to the single dose of azithromycin in treating chlamydia. Therefore, based on the study, doxycycline is highly recommended for treating chlamydia infection. Similarly, Adachi et al. (2021) report the effectiveness of azithromycin and doxycycline in treating chlamydia. The therapeutic choice and recommendation are based on the reduced risk for infection relapse; therefore, doxycycline would be preferred.

References

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Adachi, K. N., Nielsen-Saines, K., & Klausner, J. D. (2021). Chlamydia trachomatis screening and treatment in pregnancy to reduce adverse pregnancy and neonatal outcomes: A review. Frontiers in Public Health9https://doi.org/10.3389/fpubh.2021.531073

Jin, J. (2021). Screening for chlamydia and gonorrhea. JAMA326(10), 984. https://doi.org/10.1001/jama.2021.14770

Käding, N., Schmidt, N., Scholz, C., Graspeuntner, S., Rupp, J., & Shima, K. (2021). Impact of first-line antimicrobials on chlamydia trachomatis-induced changes in host metabolism and Cytokine production. Frontiers in Microbiology12https://doi.org/10.3389/fmicb.2021.676747

Macaux, L., Zemali, N., Jaubert, J., Koumar, Y., Manaquin, R., Poubeau, P., Camuset, G., Gérardin, P., & Bertolotti, A. (2020). A single dose of azithromycin for treatment of patients with asymptomatic rectal chlamydia trachomatis. Acta Dermato Venereologica100(18), adv00313. https://doi.org/10.2340/00015555-3675

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Choose a sexually transmitted disease (STD) or a disorder associated with the human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). Provide an overview of the underlying pathophysiology of the disorder as well as the available pharmacologic treatment options available. Find 2 peer-reviewed articles from the literature that evaluate the treatment of this disorder and discuss the recommendations in available guidelines. Include the name of the disorder in the subject line so that the disorder can be followed.

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