Discussion Question Essay

Discussion Question Essay

Discussion Question

Epilepsy is a central nervous system disease that affects brain activity that eventually results in seizures. Epilepsy results from the imbalance between excitation and relaxation characterized by spasms and uncontrollable muscle twitches. In some cases, the patients with the condition may become unconscious. The common signs and symptoms of epilepsy include dizziness, tingling of the limbs, staring blankly, and unresponsiveness among others. Topiramate is among the medications used in treating epilepsy, especially, those that are drug-resistant.


The mode of action for the topiramate includes increasing the GABA activity and the inhibition of the glutamate activities that result in the blockage of the neuronal excitation. Commonly, epilepsy may occur alongside migraines. Furthermore, the drug blocks voltage-dependent sodium channels which are linked with the seizure episodes. The drug is classified as an anticonvulsant and acts by reducing brain excitation. The common side effects of the topiramate include feeling sick, dizzy, and diarrhea. Patients should be closely monitored for any adverse outcomes (Bresnahan et al., 2019). Also, the dosage administered must be checked to avoid overdose. Also, prolonged use of the drug could result in slowed mental functioning.

The prescriber must understand the patients’ medical history before administering the drug as an important guideline requirement. Also, close monitoring is recommended. The drug interacts adversely with birth pills, glaucoma medications, and valproic acid. Therefore, the medication should be given alongside the stated drugs because of the possible side effects (Bresnahan et al., 2019). Finally, epilepsy is a long-term disease that requires continuous management. Proper patient education should be provided to help the patient avoid possible head injuries that could worsen their mental status.


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Bresnahan, R., Hounsome, J., Jette, N., Hutton, J. L., & Marson, A. G. (2019). Topiramate add-on therapy for drug-resistant focal epilepsy. Cochrane Database of Systematic Reviews2019(10). https://doi.org/10.1002/14651858.cd001417.pub4


please answer discussion board below, minimum 250 words thank you

Select another CNS, pain, inflammation, bone, or joint disorder from a different category than the one that you discussed in DQ1, and briefly explain the pathophysiology of that disorder. Select a drug used to treat the disorder you identified. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Discuss evidence and treatment guidelines to determine appropriate therapeutic options for a patient with your selected disorder. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.

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